Stock Market LIVE Updates: Most Asian markets down as Fed prepares latest hike

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Tokyo stocks opened lower Wednesday with investors taking cues from a cut to profit estimates by US retail giant Walmart, which helped drag down US markets. The benchmark Nikkei 225 index slipped 0.44 percent, or 120.43 points, to 27,534.78 in early trade, while the broader Topix index fell 0.31 percent, or 5.98 points, to 1,937.19.